Revive Therapeutics: Initiation report

Revive Therapeutics (CSE:RVV, OTCQB:RVVTF) is a speciality life sciences company focussed on repurposing drugs for rare and infectious diseases. The company has a pipeline comprising three main platforms:

Bucillamine for treatment of infectious diseases including COVID-19:

Bucillamine (BUC) is a medication with a well-established safety profile having been prescribed for arthritis for more than 30 years. Revive Therapeutics has been working with BUC for five years as a repurposing opportunity and has obtained two Food and Drug Administration (FDA) INDs (investigational new drug applications) with BUC to treat gout flares and cystinuria. During 2020 the company has made an IND filing concerning the use of BUC to treat COVID-19 with intellectual property around infectious diseases.

BUC has shown significant potential to reduce lung inflammation damage associated with a serious infection, and could, therefore, reduce fatalities from COVID-19. The company received a recommendation from the FDA that it skip Phase 2 trials and make an application to move immediately to Phase 3. If this trial proceeds and begins to deliver results, we believe this would be a major catalyst for the share price. We examine this opportunity on p3-5.