The health sciences group, which is developing innovative preventive therapies using organic and nature identical products, noted that venom from the Caribbean blue scorpion has been shown to impact aggressive cancers, such as in the brain.
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The firm said its research partner, via work, has whittled down four peptides to two which show the most potential for further development as therapeutic agents in the management of certain brain cancers.
The two peptides were "able to inhibit the activity of the target protein", which resulted in an obvious slowing of invasion, particularly in cancer cells, the company added.
They also displayed modest suppression of an important cancer cell marker, which has a role in promoting cancer spread/metastasis and is also associated with drug and immune resistance in brain cancer, the Vancouver-based firm said.
Accelerating the process
PreveCeutical said it was now "accelerating the process of evaluating options on how best to progress the two lead peptide drug candidates", which may include partnering to speed up pre-clinical evaluation.
"The pre-clinical outcomes, along with the company's IP coverage, would have the potential to demonstrate proof of concept and enable the company to further extend dialogue with pharma R & D / biotech companies active in the therapeutic neuro-oncology space," it noted.
"We are indeed quite excited to have accomplished further strides towards proof of concept for these innovative Nature Identical peptide therapeutics for application into the neuro-oncology therapeutic area and look forward to progressing them through proof of concept studies," said PreveCeutical's president and chief science officer Dr Mak Jawadekar.
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